The Lysosome, Elixir of Neural Stem Cell Youth.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29727677.
- Also identified by DOI 10.1016/j.stem.2018.04.017.
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Abstract
Recently in Science, Leeman et al. find that perturbing lysosomal activity of quiescent NSCs directly impedes their ability to become activated, similar to what happens during aging. Excitingly, they could rejuvenate old quiescent NSCs by enhancing the lysosome pathway, ameliorating their ability to clear protein aggregates and become activated.
Medical subject headings
- Neural Stem Cells