Relationship Between Anemia, Malaria Coinfection, and Kaposi Sarcoma-Associated Herpesvirus Seropositivity in a Population-Based Study in Rural Uganda.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 29741631.
- Also identified by DOI 10.1093/infdis/jiy274 and PMC identifier 6107741.
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Abstract
We examined anemia and malaria as risk factors for Kaposi sarcoma-associated herpesvirus (KSHV) seropositivity and antibody levels in a long-standing rural Ugandan cohort, in which KSHV is prevalent. Samples from 4134 children, aged 1-17 years, with a sex ratio of 1:1, and 3149 adults aged 18-103 years, 41% of whom were males, were analyzed. Among children, malaria infection was associated with higher KSHV prevalence (61% vs 41% prevalence among malaria infected and uninfected, respectively); malaria was not assessed in adults. Additionally, lower hemoglobin level was associated with an increased prevalence of KSHV seropositivity, both in children and in adults.
Medical subject headings
- Anemia
- Antibodies, Viral
- Herpesviridae Infections
- Herpesvirus 8, Human
- Malaria