Incorporating catechol into electroactive polypyrrole nanowires on titanium to promote hydroxyapatite formation.

Wang, Zhengao; Zeng, Jinquan; Tan, Guoxin; Liao, Jingwen; Zhou, Lei; Chen, Junqi; Yu, Peng; Wang, Qiyou et al. · Bioact Mater · 2018

basic_science · Level V

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Abstract

To improve the osteointegration property of biomedical titanium, nano-architectured electroactive coating was synthesized through the electrochemical polymerization of dopamine and pyrrole. The highly binding affinity of Ca<sup>2+</sup> to the catechol moiety of doped dopamine enabled efficient interaction between polypyrrole/polydopamine nanowires and mineral ions. The results indicate that the PPy/PDA nanowires preserved its efficient electro-activity and accelerated the hydroxyapatite deposition in a simulated body fluid. The PPy/PDA nanowires coating could be applied to promote the osteointegration of titanium implant.