Chitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings.

Mohandas, Annapoorna; Deepthi, S; Biswas, Raja; Jayakumar, R · Bioact Mater · 2018

review · Level V

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Abstract

Chitosan based nanocomposite scaffolds have attracted wider applications in medicine, in the area of drug delivery, tissue engineering and wound healing. Chitosan matrix incorporated with nanometallic components has immense potential in the area of wound dressings due to its antimicrobial properties. This review focuses on the different combinations of Chitosan metal nanocomposites such as Chitosan/nAg, Chitosan/nAu, Chitosan/nCu, Chitosan/nZnO and Chitosan/nTiO<sub>2</sub> towards enhancement of healing or infection control with special reference to the antimicrobial mechanism of action and toxicity.