Clonal Hematopoiesis: A New Layer in the Liquid Biopsy Story in Lung Cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29748181.
- Also identified by DOI 10.1158/1078-0432.CCR-18-0969.
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Abstract
Cell-free DNA (cfDNA) is a unique biospecimen that contains multiple sources of DNA, including tumor, germline, fetal, and others. Clonal hematopoiesis, a process that leads to expansion of mutations in peripheral blood cells, is an additional source of DNA that adds a layer of complexity when interpreting results. <i>Clin Cancer Res; 24(18); 4352-4. ©2018 AACR</i><i>See related article by Hu et al., p. 4437</i>.
Medical subject headings
- Cell-Free Nucleic Acids
- Lung Neoplasms