Clinical narrative: autoimmune hepatitis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 29755125.
- Also identified by DOI 10.1038/s41395-018-0058-z.
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Abstract
Autoimmune hepatitis (AIH) is an inflammatory liver disease that is characterized by circulating autoantibodies, hypergammaglobulinemia, and a lymphoplasmocytic infiltration with interface hepatitis on liver biopsy. Treatment with corticosteroids and other immunosuppressive agents is effective and early diagnosis can result in near-normal life expectancy. Untreated patients, however, can progress to cirrhosis and liver failure. The clinical presentation is heterogeneous and may pose diagnostic and therapeutic dilemmas. This case-based review will address the diagnosis and management of this disease, in addition to difficult but commonly encountered clinical scenarios.
Medical subject headings
- Hepatitis, Autoimmune