ConSpeciFix: classifying prokaryotic species based on gene flow.
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- Record sourced from PubMed, PMID 29771275.
- Also identified by DOI 10.1093/bioinformatics/bty400 and PMC identifier 6198855.
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Abstract
Classification of prokaryotic species is usually based on sequence similarity thresholds, which are easy to apply but lack a biologically-relevant foundation. Here, we present ConSpeciFix, a program that classifies prokaryotes into species using criteria set forth by the Biological Species Concept, thereby unifying species definition in all domains of life. ConSpeciFix's webserver is freely available at www.conspecifix.com. The local version of the program can be freely downloaded from https://github.com/Bobay-Ochman/ConSpeciFix. ConSpeciFix is written in Python 2.7 and requires the following dependencies: Usearch, MCL, MAFFT and RAxML.
Medical subject headings
- Gene Flow
- Software