Neurons Are the Inflammatory Problem.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29775588.
- Also identified by DOI 10.1016/j.cell.2018.05.005.
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Abstract
The discovery that reflex neuronal circuits control immunity provided a new mechanistic understanding of infection and injury. Pinho-Ribeiro et al. (2018) report that lethal tissue destruction from streptococcal necrotizing fasciitis ("flesh-eating disease") occurs because sensory neurons reflexively inhibit frontline immune responses.
Medical subject headings
- Fasciitis, Necrotizing
- Streptococcal Infections