Rotavirus Vaccination Is Associated With Reduced Seizure Hospitalization Risk Among Commercially Insured US Children.

Burke, Rachel M; Tate, Jacqueline E; Dahl, Rebecca Moritz; Aliabadi, Negar; Parashar, Umesh D · Clin Infect Dis · 2018

retrospective_cohort · Level III

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Abstract

Rotavirus commonly causes diarrhea but can also cause seizures. Analysis of insurance claims for 1773295 US children with 2950 recorded seizures found that, compared to rotavirus-unvaccinated children, seizure hospitalization risk was reduced by 24% (95% confidence interval [CI], 13%-33%) and 14% (95% CI, 0%-26%) among fully and partially rotavirus-vaccinated children, respectively.

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