Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.

Parks, Tom; Wilson, Clare; Curtis, Nigel; Norrby-Teglund, Anna; Sriskandan, Shiranee · Clin Infect Dis · 2018

meta_analysis · Level I

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Abstract

We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.

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