Targeted Therapies for Brain Tumors: Will They Ever Deliver?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29798907.
- Also identified by DOI 10.1158/1078-0432.CCR-18-0855.
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Abstract
The strategy of using biologically targeted therapeutics for cancer has yet to translate into effective treatment of gliomas. The neuro-oncology community is beginning to recognize that phase 0 studies should be performed to account for the impact of the blood-brain barrier on the ability of a therapeutic to reach its target(s). <i>Clin Cancer Res; 24(16); 3790-1. ©2018 AACR</i><i>See related article by Sanai et al., p. 3820</i>.
Medical subject headings
- Brain Neoplasms
- Glioblastoma