The Positives and Negatives of NPR: A Unifying Model for Salicylic Acid Signaling in Plants.

Innes, Roger · Cell · 2018

basic_science · Level V

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Abstract

Salicylic acid (SA) is a potent inducer of defense gene expression in plants, but how SA activates transcription has been controversial. In this issue of Cell, Ding et al. show that the SA-binding proteins NPR3 and NPR4 function as transcriptional co-repressors, with this activity being blocked by SA.

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