Spotlight on Glycolysis: A New Target for Cord Blood Expansion.

Patterson, Andrea M; Pelus, Louis M · Cell Stem Cell · 2018

editorial · Level V

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Abstract

Umbilical cord blood (UCB) is a highly valuable but low-quantity source of hematopoietic stem cells (HSCs) for life-saving transplantations. Recently in Nature Medicine, Guo et al. (2018) found that antagonism of a glycolysis-blocking pathway enhances ex vivo expansion of long-term HSCs from human UCB.

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