Kidney surveillance in the spotlight: contrast-induced acute kidney injury illuminated.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29863496.
- Also identified by DOI 10.1172/JCI121741 and PMC identifier 6025966.
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Abstract
Acute kidney injury comprises a heterogeneous group of conditions characterized by a sudden decrease in renal function over hours to days. Contrast-induced acute kidney injury (CI-AKI) is caused by radiographic contrast agents used in diagnostic imaging. In the current issue of the JCI, Lau et al. use a mouse model of CI-AKI to study the role of resident and infiltrating phagocytes, recruited leukocytes, and tubular cells in the immune surveillance response to contrast agents. This study has the potential to provide innovative therapies for human CI-AKI.
Medical subject headings
- Acute Kidney Injury
- Dipeptidases