Obesity Protects Cancer from Drugs Targeting Blood Vessels.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 29874563.
- Also identified by DOI 10.1016/j.cmet.2018.05.014.
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Abstract
Drugs that target angiogenesis are commonly used for treating various cancers, but their clinical benefits are limited. In a recent Science Translational Medicine article, Incio et al. (2018) provide mechanistic insight on the role of obesity in the development of anti-VEGF drug resistance in human patients and murine models of breast cancer.
Medical subject headings
- Breast Neoplasms
- Vascular Endothelial Growth Factor A