MUC5AC Levels Associated With Respiratory Syncytial Virus Disease Severity.

Rajan, Devi; O'Keefe, Evan L; Travers, Curtis; McCracken, Courtney; Geoghegan, Sarah; Caballero, Mauricio T; Acosta, Patricio L; Polack, Fernando et al. · Clin Infect Dis · 2018

cross_sectional · Level IV

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Abstract

To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.

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