Increased antibiotic duration improves reoperation free survival after total hip arthroplasty irrigation and debridement.

Bene, Nicholas; Li, Xing; Nandi, Sumon · J Orthop · 2018

retrospective_cohort · Level III

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Abstract

We aimed to determine if reoperation-free survival following irrigation and debridement (I&D) with head and liner exchange of infected primary THA is affected by: 1) postoperative antibiotic duration; 2) patient characteristics; 3) infecting organism; or 4) postoperative versus hematogenous infection. Revision THAs from 2006 to 2012 (n = 1184) were observed; 26 underwent I&D with head and liner exchange with mean 4.1-year follow-up. Patients with reoperation for infection (n = 2) versus those without reoperation (n = 24) were analyzed. Increased postoperative antibiotic therapy duration (p = 0.0333) decreased risk of reoperation for infection. Chronic antibiotic suppression should be considered following THA I&D with head and liner exchange.

Anatomy