Toward Precision Medicine for Neurological and Neuropsychiatric Disorders.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 29887317.
- Also identified by DOI 10.1016/j.stem.2018.05.019.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The genetic complexity, clinical variability, and inaccessibility of affected tissue in neurodegenerative and neuropsychiatric disorders have largely prevented the development of effective disease-modifying therapeutics. A precision medicine approach that integrates genomics, deep clinical phenotyping, and patient stem cell models may facilitate identification of underlying biological drivers and targeted drug development.
Medical subject headings
- Mental Disorders
- Nervous System Diseases
- Precision Medicine
- Stem Cell Transplantation
- Stem Cells