Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 29892063.
- Also identified by DOI 10.1038/s41591-018-0026-6 and PMC identifier 6092240.
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Abstract
Antiretroviral therapy during the earliest stage of acute HIV infection (Fiebig I) might minimize establishment of a latent HIV reservoir and thereby facilitate viremic control after analytical treatment interruption. We show that 8 participants, who initiated treatment during Fiebig I and were treated for a median of 2.8 years, all experienced rapid viral load rebound following analytical treatment interruption, indicating that additional strategies are required to control or eradicate HIV.
Medical subject headings
- Antiretroviral Therapy, Highly Active
- HIV Infections
- HIV-1
- RNA, Viral