Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 29893821.
- Also identified by DOI 10.1093/cid/ciy486 and PMC identifier 6293039.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A Ugandan child with an unexplained encephalitis was investigated using viral metagenomics. Several sequences from all segments of a novel orthobunyavirus were found. The S-segment, used for typing, showed 41% amino acid diversity to its closest relative. The virus was named Ntwetwe virus, after the hometown of the patient.
Medical subject headings
- Bunyaviridae Infections
- Cerebrospinal Fluid
- Encephalitis, Viral
- Orthobunyavirus