Porphysomes: Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model (Adv. Healthcare Mater. 14/2015).
basic_science · Level V
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- Also identified by DOI 10.1002/adhm.201570084.
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Abstract
On page 2164, J. Chen, J.C. Irish, G. Zheng, and co-workers show how <sup>64</sup> Cu-porphysome nanoparticles enable superior delineation of neoplastic tissues, metastatic lymph nodes, and vascular drainage on a head and neck cancer orthotopic rabbit model by PET imaging. Their selective fluorescence activation in tumor and metastatic lymph nodes permits intraoperative fluorescence guided surgeries.