Visible Machine Learning for Biomedicine.

Yu, Michael K; Ma, Jianzhu; Fisher, Jasmin; Kreisberg, Jason F; Raphael, Benjamin J; Ideker, Trey · Cell · 2018

review · Level V

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Abstract

A major ambition of artificial intelligence lies in translating patient data to successful therapies. Machine learning models face particular challenges in biomedicine, however, including handling of extreme data heterogeneity and lack of mechanistic insight into predictions. Here, we argue for "visible" approaches that guide model structure with experimental biology.

Medical subject headings