Fecal Calprotectin to Detect Inflammatory Bowel Disease in Juvenile Idiopathic Arthritis.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 29907671.
- Also identified by DOI 10.3899/jrheum.171200.
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Abstract
This study aimed to test fecal calprotectin (FC) as a screening tool to identify inflammatory bowel disease (IBD) among patients with juvenile idiopathic arthritis (JIA). FC level < 100 g/kg was considered normal. Patients with 2 consecutive FC dosage ≥ 100 g/kg underwent endoscopic evaluation. There were 113 patients with JIA enrolled. FC was raised in 7 patients out of 113. All patients had IBD. In 3/7 patients, high FC levels were the only sign consistent with IBD. FC is a useful, economical, and noninvasive diagnostic tool to identify JIA patients with underlying IBD.
Medical subject headings
- Arthritis, Juvenile
- Feces
- Inflammatory Bowel Diseases
- Leukocyte L1 Antigen Complex