Development of Mobile Laboratory for Viral Hemorrhagic Fever Detection in Africa.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 29917112.
- Also identified by DOI 10.1093/infdis/jiy362 and PMC identifier 6173574.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A mobile laboratory transportable on commercial flights was developed to enable local response to viral hemorrhagic fever outbreaks. The development progressed from use of mobile real-time reverse-transcription polymerase chain reaction to mobile real-time recombinase polymerase amplification. In this study, we describe various stages of the mobile laboratory development. A brief overview of mobile laboratory deployments, which culminated in the first on-site detection of Ebola virus disease (EVD) in March 2014, and their successful use in a campaign to roll back EVD cases in Conakry in the West Africa Ebola virus outbreak are described. The developed mobile laboratory successfully enabled local teams to perform rapid disgnostic testing for viral hemorrhagic fever.
Medical subject headings
- Hemorrhagic Fever, Ebola
- Laboratories
- Mobile Health Units
- Point-of-Care Systems