The net effect of ANCA on neutrophil extracellular trap formation.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 29933842.
- Also identified by DOI 10.1016/j.kint.2018.03.010.
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Abstract
The formation of neutrophil extracellular traps induced by antineutrophil cytoplasmic autoantibodies has been implicated in the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis. Kraaij et al. now provide evidence that excessive neutrophil extracellular trap formation in vitro induced by sera from patients with antineutrophil cytoplasmic autoantibody-associated vasculitis is associated with active disease but is not dependent on the presence of antineutrophil cytoplasmic autoantibodies.
Medical subject headings
- Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
- Extracellular Traps