The Introduction of Innovations in Neurovascular Care: Patient Selection and Randomized Allocation.

Fahed, Robert; Darsaut, Tim E; Raymond, Jean · World Neurosurg · 2018

review · Level V

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Abstract

Most neurovascular innovations have been introduced by using case series followed by observational studies. A better approach would be a pragmatic randomized trial. Two important aspects of trial design, patient selection and randomized allocation, remain poorly understood. We discuss the role trial methodology can play in the protection of patients being offered innovative treatments.

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