Associations Between Cardiorespiratory Fitness and Arterial Stiffness in Ankylosing Spondylitis: A Cross-sectional Study.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 29961684.
- Also identified by DOI 10.3899/jrheum.170726.
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Abstract
To assess associations between cardiorespiratory fitness (CRF), measured as peak oxygen uptake (VO<sub>2</sub>peak), and cardiovascular disease (CVD) risk, measured by arterial stiffness, in patients with ankylosing spondylitis (AS). VO<sub>2</sub>peak was assessed by a maximal walking test on a treadmill. Arterial stiffness was measured noninvasively (Sphygmocor apparatus). Cross-sectional associations between VO<sub>2</sub>peak and arterial stiffness were analyzed using backward multivariable linear regression. Among 118 participating patients, there were significant inverse associations between VO<sub>2</sub>peak and arterial stiffness, independent of traditional CVD risk factors and measures of disease activity. Reduced CRF may be related to increased risk of CVD in AS.
Medical subject headings
- Cardiorespiratory Fitness
- Spondylitis, Ankylosing
- Vascular Stiffness