Th17 Cells in Parkinson's Disease: The Bane of the Midbrain.
editorial · Level V
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- Record sourced from PubMed, PMID 29979991.
- Also identified by DOI 10.1016/j.stem.2018.06.016 and PMC identifier 7839142.
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Abstract
Emerging data implicate potential roles for T cells in Parkinson's disease (PD); however, direct evidence for human T cells in PD-associated neurodegeneration has been lacking. In this issue of Cell Stem Cell, Sommer et al. (2018) demonstrate that IL-17-producing T cells from sporadic PD patients promote cell death of patient iPSC-derived midbrain neurons.
Medical subject headings
- Parkinson Disease