Postmitotic Fate Refinement in the Subplate.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29979992.
- Also identified by DOI 10.1016/j.stem.2018.06.017.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
How is the astonishing diversity of cortical neurons specified? In this issue of Cell Stem Cell, Ozair et al. (2018) leverage hPSC neural differentiation to show that projection neurons undergo prolonged sojourns in the subplate before migrating to deep layers, suggesting that pausing in the subplate may enable integration of intrinsic and extrinsic cues during postmitotic fate refinement.
Medical subject headings
- Axons
- Neurons