Genotoxic Lemons Become Epigenomic Lemonade.
editorial · Level V
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- Record sourced from PubMed, PMID 29979994.
- Also identified by DOI 10.1016/j.stem.2018.06.007.
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Abstract
Active regulatory elements in hematopoietic stem cells (HSCs) are incompletely characterized, since extant approaches immunophenotypically define and isolate rare HSCs. In the current issue of Cell Stem Cell, Wünsche et al. (2018) use γ-retroviral insertion sites from a human gene therapy trial to identify the active enhancer landscape of functionally characterized HSCs.
Medical subject headings
- Epigenomics
- Hematopoietic Stem Cells