Chronic Kidney Disease Risk in African and Caribbean Populations With HIV.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 29982487.
- Also identified by DOI 10.1093/infdis/jiy397 and PMC identifier 6195659.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We conducted an observational cohort study of end-stage kidney disease (ESKD) in >7000 African and Caribbean people with HIV in the UK. Using Poisson regression and East Africans as the reference group, the adjusted incidence rate ratio (95% confidence interval) of ESKD was 3.14 (1.26-7.84) in Southern Africans, 6.35 (2.53-15.96) in West Africans, and 5.26 (1.91-14.43) in Caribbeans. Higher CD4 cell count and suppressed HIV replication were associated with reduced risk of ESKD. The risk of ESKD varied among HIV-positive people of African heritage, with the highest rates observed in those of West African descent.
Medical subject headings
- Black People
- HIV Infections
- Renal Insufficiency, Chronic