RNAvista: a webserver to assess RNA secondary structures with non-canonical base pairs.
basic_science · Level V
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- Record sourced from PubMed, PMID 29985979.
- Also identified by DOI 10.1093/bioinformatics/bty609 and PMC identifier 6298044.
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Abstract
In the study of 3D RNA structure, information about non-canonical interactions between nucleobases is increasingly important. Specialized databases support investigation of this issue based on experimental data, and several programs can annotate non-canonical base pairs in the RNA 3D structure. However, predicting the extended RNA secondary structure which describes both canonical and non-canonical interactions remains difficult. Here, we present RNAvista that allows predicting an extended RNA secondary structure from sequence or from the list enumerating canonical base pairs only. RNAvista is implemented as a publicly available webserver with user-friendly interface. It runs on all major web browsers. http://rnavista.cs.put.poznan.pl.
Medical subject headings
- Base Pairing
- Nucleic Acid Conformation
- RNA
- Software