Model-Based Assessment of f-Wave Signal Quality in Patients With Atrial Fibrillation.

Abstract

OBJECTIVE: The detection and analysis of atrial fibrillation (AF) in the ECG is greatly influenced by signal quality. The present study proposes and evaluates a model-based f-wave signal quality index (SQI), denoted , for use in the QRST-cancelled ECG signal. METHODS: is computed using a harmonic f-wave model, allowing for variation in frequency and amplitude. The properties of  are evaluated on both f-waves and P-waves using 378 12-lead ECGs, 1875 single-lead ECGs, and simulated signals. RESULTS: decreases monotonically when noise is added to f-wave signals, even for noise which overlaps spectrally with f-waves. Moreover, is shown to be closely associated with the accuracy of AF frequency estimation, where implies accurate estimation. When  is used as a measure of f-wave presence, AF detection performance improves: the sensitivity increases from 97.0% to 98.1% and the specificity increases from 97.4% to 97.8% when compared to the reference detector. CONCLUSION: The proposed SQI represents a novel approach to assessing f-wave signal quality, as well as to determining whether f-waves are present. SIGNIFICANCE: The use of  improves the detection of AF and benefits the analysis of noisy ECGs.