Bone Marrow-Derived and Adipose-Derived Mesenchymal Stem Cell Therapy in Primary Knee Osteoarthritis: A Narrative Review.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 30010050.
- Also identified by DOI 10.1016/j.pmrj.2018.06.019.
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Abstract
Regenerative medicine in the context of musculoskeletal injury is a broad term that offers potential therapeutic solutions to restore or repair damaged tissue. The current focus in recent literature and clinical practice has been on cell based therapy. In particular, much attention has been centered on autologous bone marrow concentrate and adipose-derived mesenchymal stem cells (MSCs) for cartilage and tendon disorders. This article provides an overview of MSC-derived therapy and offers a comprehensive review of adipose- and bone marrow-derived MSC therapy in primary knee osteoarthritis. LEVEL OF EVIDENCE: IV.
Medical subject headings
- Adipose Tissue
- Bone Marrow Cells
- Bone Marrow Transplantation
- Mesenchymal Stem Cell Transplantation
- Osteoarthritis, Knee
- Regenerative Medicine