Changing the Guard at a Prostate Cancer SNP.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30053422.
- Also identified by DOI 10.1016/j.cell.2018.07.014.
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Abstract
The molecular underpinnings of a prostate-cancer-associated SNP are investigated in a pair of papers in this issue of Cell. Together, Gao et al. and Hua et al. paint a picture of competition between transcription factors that, in turn, toggle the function of a regulatory region from a promoter to an enhancer and induce a switch in noncoding RNA isoforms.
Medical subject headings
- Prostatic Neoplasms
- RNA, Long Noncoding