Intestinal Crypts Assume the Fetal Position in Response to Injury.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30075126.
- Also identified by DOI 10.1016/j.stem.2018.07.013.
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Abstract
Distinct stem/progenitor cells generate intestinal epithelium during fetal and postnatal life. In a recent issue of Nature, Nusse and Savage et al. use helminth infection to show that Lgr5<sup>+</sup> intestinal stem cells are replaced by fetal-like progenitors following injury, suggesting that some fetal developmental pathways are repurposed during injury-induced tissue regeneration.
Medical subject headings
- Helminths
- Stem Cell Niche