Sweet Killers: NK Cells Need Glycolysis to Kill Tumors.
Where this comes from
- Record sourced from PubMed, PMID 30089237.
- Also identified by DOI 10.1016/j.cmet.2018.07.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype.
Medical subject headings
- Cytotoxicity, Immunologic
- Lung Neoplasms