Cyclical Dedifferentiation and Redifferentiation of Mammary Adipocytes.

Corsa, Callie A S; MacDougald, Ormond A · Cell Metab · 2018

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Abstract

Adipocytes are generally thought to be terminally differentiated cells; however, recent evidence suggests a subset may have greater plasticity in certain contexts. In this issue of Cell Metabolism, Wang et al. (2018) demonstrate a novel capacity for mammary adipocytes to dedifferentiate into preadipocyte-like precursors during lactation and redifferentiate upon weaning.

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