Enhancing Therapy: It's about Time.

Brown, Myles · Cell · 2018

editorial · Level V

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Abstract

How diet and obesity impact diurnal changes in physiology remains unclear. In this issue of Cell, Guan et al. report that diet-induced obesity modulates the activity of circadian gene enhancers including those regulating lipid metabolism and show that the efficacy of lipid-lowering drugs depends on the time of administration.

Medical subject headings