Viral Teamwork Pushes CRISPR to the Breaking Point.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30096306.
- Also identified by DOI 10.1016/j.cell.2018.07.025.
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Abstract
Viruses have evolved inhibitors to counteract the CRISPR immune response, but they are not fully potent and need some time to be expressed after the beginning of infection. In this issue of Cell, Borges et al. and Landsberger et al. show that sequential infection gradually immunosuppresses the host to allow effective CRISPR inhibition.
Medical subject headings
- Bacteriophages
- Viruses