Aprepitant for the Treatment of Pruritus in Sézary Syndrome: A Randomized Crossover Clinical Trial.

Zic, John A; Straka, Brittany T; McGirt, Laura Y; Nian, Hui; Yu, Chang; Brown, Nancy J · JAMA Dermatol · 2018

rct · Level II

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Abstract

This randomized clinical trial assesses whether treatment with the neurokinin 1 receptor antagonist aprepitant decreases pruritus vs placebo in patients with Sézary syndrome.

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