Neonate-omics: Charting the Unknown Immune Response in Early Life.

Jennewein, Madeleine F; Butler, Audrey L; Alter, Galit · Cell · 2018

review · Level V

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Abstract

The study of neonatal immunology has been hampered by lack of access to infant samples. Novel sample sparing methods and systems-wide approaches have uniquely expanded this field, demonstrating that newborn immunity varies widely but converges over the first 3 months of life. During this important time window, environmental and genetic factors impact the infant immune system and can influence lifelong immunity.

Medical subject headings