Nanoparticles for CRISPR-Cas9 delivery.

Glass, Zachary; Li, Yamin; Xu, Qiaobing · Nat Biomed Eng · 2017

basic_science · Level V

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Abstract

The DNA mutation that causes Duchenne muscular dystrophy in mice can be corrected, with minimal off-target effects, by gold nanoparticles carrying the CRISPR components.