HLA-IMPUTER: an easy to use web application for HLA imputation and association analysis using population-specific reference panels.
Where this comes from
- Record sourced from PubMed, PMID 30169743.
- Also identified by DOI 10.1093/bioinformatics/bty730.
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Abstract
HLA allele imputation from SNP genotypes has become increasingly useful, but its accuracy is heavily dependent on the reference panels used. HLA-IMPUTER implements HIBAG algorithm for HLA imputation with different population specific reference panels, including a new Han Chinese reference panel derived from 10 689 samples. We provide a convenient platform for researchers to impute HLA alleles and perform association analysis. http://wyanglab.org: 3838/RefPanelWebsite/. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Polymorphism, Single Nucleotide
- Software