The use of electrochemical techniques to evaluate the corrosion performance of metallic biomedical materials and devices.

Abstract

The corrosion performance of metallic biomedical materials and devices is commonly evaluated using electrochemical techniques. Although test standards involving such techniques have been released to address some forms of corrosion, a key issue is application of the results with regard to use of an implantable device in vivo. This review focuses on nitinol, 316L/LVM stainless steel, and Co-Cr alloys and is intended to provide some perspective on the significance of results from tests concerning general corrosion, localized corrosion, galvanic corrosion, and fretting corrosion of these alloys in simulated physiological solutions. It also examines the factors that could cause differences in the corrosion performance between in vitro and in vivo exposure, with the goal of providing some rationale for applying electrochemical characteristics obtained from the tests to predict the corrosion performance in vivo. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B: 1189-1198, 2019.