A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
other · Level V
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- Record sourced from PubMed, PMID 30192759.
- Also identified by DOI 10.1371/journal.pone.0201643 and PMC identifier 6128454.
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Abstract
The Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galenic characteristics for topical application. It is also useful to track stability studies by comparing the diagrams, which allows to measure the impact of subjecting the formulation to different conditions and times to be examined. In this study, the Semi-solid Control Diagram (SSCD) is used as an instrument for studying and evaluating semi-solid pharmaceutical dosage forms, by comparing several different semisolid preparations (lipogels). With these results, the tool is validated and the best formulation has been discriminated from the others.
Medical subject headings
- Dosage Forms
- Excipients
- Pharmaceutical Preparations
- Technology, Pharmaceutical