Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin-positive Staphylococcus aureus Colonization in African Pygmies.

Schaumburg, Frieder; Witten, Anika; Flamen, Arnaud; Stoll, Monika; Alabi, Abraham S; Kremsner, Peter G; Löffler, Bettina; Zipfel, Peter F et al. · Clin Infect Dis · 2019

cross_sectional · Level IV

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Abstract

Panton-Valentine leukocidin (PVL) is common in African Staphylococcus aureus and can be associated with skin and soft tissue infection. PVL-positive S. aureus colonization is associated with a variant of complement receptor 5a, the cellular target of the lukS PVL subunit.

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