Freeing Yeast from Alcohol Addiction (Just) to Make (It) Fat Instead.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30193107.
- Also identified by DOI 10.1016/j.cell.2018.08.024.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Synthetically re-designing eukaryotic metabolism has proven immensely challenging, raising the question of whether evolution has metabolically hardwired eukaryotic cells. Yu et al. now report that, through orchestrating multiple genetic changes and laboratory evolution, Saccharomyces metabolism can be reprogrammed from its evolutionary objective of producing ethanol to produce large amounts of free fatty acids.
Medical subject headings
- Alcoholism