Outbreak of Hypervirulent Multidrug-resistant Klebsiella variicola Causing High Mortality in Neonates in Bangladesh.

Farzana, Refath; Jones, Lim S; Rahman, Md Anisur; Andrey, Diego O; Sands, Kirsty; Portal, Edward; Watkins, W John; Pervin, Monira et al. · Clin Infect Dis · 2019

case_series · Level IV

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Abstract

We report a clonal outbreak of multidrug-resistant (MDR) Klebsiella variicola (sequence type [ST] 771) in a Bangladeshi neonatal unit from October 2016 to January 2017, associated with high mortality (54.5%). During the outbreak, K. variicola ST771 acquired an MDR plasmid harboring blaNDM-1, linked to high exposure to ceftriaxone and amikacin.

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