Endoscopic Resection Followed by Proton Therapy With Pencil Beam Scanning for Skull Base Tumors.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 30208224.
- Also identified by DOI 10.1002/lary.27512 and PMC identifier 6414275.
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Abstract
For patients who require postoperative radiotherapy after endoscopic resection of skull base tumors, proton therapy with pencil beam scanning (PBS) may allow sparing of normal tissue compared to intensity-modulated photon radiation (IMRT). We compared PBS and IMRT radiation plans in the preoperative and postoperative settings for two patients with advanced skull base tumors following endoscopic resection. The benefits of PBS over IMRT appear greater in the postoperative setting following endoscopic resection with improved sparing of critical organs at risk. The multidisciplinary approach of endoscopic resection followed by PBS represents a treatment paradigm with potential for improvements in toxicity reduction. Laryngoscope, 129:1313-1317, 2019.
Medical subject headings
- Endoscopy
- Neurosurgical Procedures
- Proton Therapy
- Radiotherapy, Intensity-Modulated
- Skull Base Neoplasms